PHYSIOLOGY
SYNAPTIC PHYSIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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True
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False
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Either A or B
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None of the above
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Detailed explanation-1: -Answer and Explanation: The statement “ In myelinated axons, the voltage-regulated sodium channels are concentrated at the nodes of Ranvier” is true.
Detailed explanation-2: -Voltage-dependent sodium channels are uniformly distributed along unmyelinated axons, but are highly concentrated at nodes of Ranvier in myelinated axons.
Detailed explanation-3: -[2] The nodes contain high concentrations of voltage-gated sodium ion channels, responsible for raising membrane voltage during the creation of an all-or-nothing action potential.
Detailed explanation-4: -We point out that unmyelinated axons have voltage-gated sodium channels along the entire length of the membrane. In contrast, myelinated axons have voltage-gated sodium channels only in the nodal spaces.
Detailed explanation-5: -The nodes of Ranvier are specialized axonal segments that lack myelin, allowing the saltatory conduction of action potentials.