PHYSIOLOGY
SYNAPTIC PHYSIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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what is the function of Calcium during a skeletal muscle contraction?
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connecting to H zone
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connecting to troponin
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connecting to myofibril
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connecting to myosin
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Explanation:
Detailed explanation-1: -Calcium triggers contraction by reaction with regulatory proteins that in the absence of calcium prevent interaction of actin and myosin. Two different regulatory systems are found in different muscles.
Detailed explanation-2: -(2) Calcium binds to troponin C, which induces a conformational change in the troponin complex. This causes tropomyosin to move deeper into the actin groove, revealing the myosin-binding sites.
Detailed explanation-3: -Troponin (Tn) is the sarcomeric Ca2+ regulator for striated (skeletal and cardiac) muscle contraction. On binding Ca2+ Tn transmits information via structural changes throughout the actin-tropomyosin filaments, activating myosin ATPase activity and muscle contraction.
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