MEDICAL PHYSIOLOGY

PHYSIOLOGY

SYNAPTIC PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which is a negative feedback mechanism in the menstrual cycle?
A
Follicle stimulating hormone inhibits estrogen
B
Estrogen inhibits luteinizing hormone
C
Estrogen inhibits follicle stimulating hormone
D
Progesterone inhibits estrogen
Explanation: 

Detailed explanation-1: -Low levels of E2 and P cause negative feedback to inhibit FSH and LH secretion.

Detailed explanation-2: -In turn, these hormones act on the hypothalamus and pituitary gland to reduce the release of gonadotrophin-releasing hormone and follicle stimulating hormone (negative feedback). This causes a fall in FSH, which prevents too many follicles developing each cycle.

Detailed explanation-3: -The GnRH signals the pituitary gland to produce follicle-stimulating hormone (FSH). FSH triggers the ovaries to produce the hormone estrogen. High levels of estrogen inhibit the production of GnRH. This causes the pituitary gland to make less FSH, which causes ovaries to make less estrogen.

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