MEDICAL PHYSIOLOGY

Detailed explanation-1: -Pathways of Anaerobic Metabolism. Anaerobic metabolism, which can be defined as ATP production without oxygen (or in the absence of oxygen), occurs by direct phosphate transfer from phosphorylated intermediates, such as glycolytic intermediates or creatine phosphate (CrP), to ADP forming ATP.

Detailed explanation-2: -The anaerobic pathway utilises pyruvate, the final product of glycolysis. Without the functioning ETC there is an excess of NADH and pyruvate. Pyruvate is subsequently reduced to lactate (lactic acid) by NADH, yielding NAD+. This reaction is catalyzed by the enzyme lactate dehydrogenase.