NEET BIOLOGY

Detailed explanation-1: -“Our study indicates that 2 types of brain damage occur in prion diseases: abnormal prion protein plaques that destroy brain blood vessels and displace brain tissue, and abnormal prion protein without plaques that leads to the sponge-like damage to nerve cells, ” says lead author Dr.

Detailed explanation-2: -Prion diseases are transmissible, untreatable, and fatal brain diseases of mammals. Their cause is highly unusual: The host’s normal prion protein can, for unknown reasons, malfunction and assemble into structured aggregates called prions that cause infectious brain disease.

Detailed explanation-3: -While chemicals may not destroy a prion or render it inactive, prions may be manually removed or diluted with a disinfectant and scrubbing.

Detailed explanation-4: -Prions cannot be destroyed by boiling, alcohol, acid, standard autoclaving methods, or radiation. In fact, infected brains that have been sitting in formaldehyde for decades can still transmit spongiform disease.