NEET BIOLOGY

Detailed explanation-1: -The term “prion” is derived from proteinacious infectious particles and refers to the pathogen that causes transmissible spongiform encephalopathies (TSEs).

Detailed explanation-2: -"This evidence has led to the now widely accepted prion theory, which states that the cellular protein PrP is the sole causative agent of prion diseases; there is no nucleic acid involved.

Detailed explanation-3: -Prion protein, shown in red, can become infectious and cause neurodegenerative disease.

Detailed explanation-4: -Prions, a term derived from the phrase “proteinaceous infectious particle” (1), are the pathogens that cause a group of fatal zoonotic transmissible spongiform encephalopathies (TSEs) also known as prion diseases.

Detailed explanation-5: -The term “prions” refers to abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins called prion proteins that are found most abundantly in the brain.