NEET BIOLOGY

Detailed explanation-1: -Viral replication is critical for a virus’s ability to infect its hosts and spread. Because of this, it is a critical aspect of viral pathogenicity to understand.

Detailed explanation-2: -Viral genome replication, i.e. the synthesis of a full-length positive-sense copy of the genome and the subsequent generation of progeny negative-strands, is catalyzed by the same polymerase that directs transcription.

Detailed explanation-3: -Key Points. Viral replication involves six steps: attachment, penetration, uncoating, replication, assembly, and release. During attachment and penetration, the virus attaches itself to a host cell and injects its genetic material into it.

Detailed explanation-4: -Assembly: After de novo synthesis of viral genome and proteins, which can be post-transrciptionally modified, viral proteins are packaged with newly replicated viral genome into new virions that are ready for release from the host cell. This process can also be referred to as maturation.