NEET BIOLOGY

Detailed explanation-1: -Reverse transcriptase is central to the infectious nature of retroviruses, several of which cause disease in humans, including human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS), and human T-cell lymphotrophic virus I (HTLV-I), which causes leukemia.

Detailed explanation-2: -The human immunodeficiency virus (HIV) uses reverse transcriptase to make double-stranded RNA copies of its DNA genome.-A retrovirus such as HIV has an RNA genome and uses reverse transcriptase to make double-stranded DNA copies of the genome, which can then be integrated into the host cell’s genome.

Detailed explanation-3: -An enzyme found in HIV (and other retroviruses). HIV uses reverse transcriptase (RT) to convert its RNA into viral DNA, a process called reverse transcription.

Detailed explanation-4: -Reverse transcriptases (RTs) play a major role in the replication of Retroviridae, Metaviridae, Pseudoviridae, Hepadnaviridae and Caulimoviridae.

Detailed explanation-5: -Reverse-transcribing viruses replicate using reverse transcription, a process for making DNA from RNA templates. Their genomes can be either RNA or DNA. Retroviruses are ssRNA viruses that replicate through a DNA intermediate, thus requiring a virus-encoded RNA-dependent DNA polymerase (reverse transcriptase).