Chemicals, such as atrazine & bisphenol A (BPA), that mimic hormones and can lead to birth defects, developmental disorders, and gender imbalances in fish and other species.

HUMAN HEALTH AND DISEASE

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

A	teratogens
B	endocrine disruptors
C	mutagens
D	carcinogens

Explanation:

Detailed explanation-1: -BPA is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). BPA absorption into the body can result in the development of metabolic disorders such as low sex-specific neurodevelopment, immune toxicity, neurotoxicity and interference of cellular pathway.

Detailed explanation-2: -BPA can mimic estrogen to interact with estrogen receptors and , leading to changes in cell proliferation, apoptosis, or migration and thereby, contributing to cancer development and progression.

Detailed explanation-3: -BPA is an endocrine (hormone) disruptor. BPA mimics the structure and function of the hormone estrogen. Due to its estrogen-like shape, BPA can bind to estrogen receptors and influence normal bodily processes. These include growth, cell repair, fetal development, and reproduction.

Detailed explanation-4: -BPA is classified as an Endocrine Disrupting Chemical (EDC) because it can act as a xenoestrogen. EDCs interfere and prevent the binding of natural hormones to their receptors and/or can act as a hormone mimics; consequently, they exaggerate the effects of endogenous hormones [2, 8].

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NEET BIOLOGY

BIOLOGY IN HUMAN WELFARE

HUMAN HEALTH AND DISEASE