BIOLOGY IN HUMAN WELFARE
MICROBES IN HUMAN WELFARE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Trichoderma polysporum (a fungus)
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Bacillus (a bacterium)
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Aspergillus (a fungus)
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all of these
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Detailed explanation-1: -Cyclosporine A is widely produced by submerged fermentation of aerobic fungi identified as Trichoderma polysporum[4] but currently identified as Tolypocladium inflatum[5]. Since its discovery, very few studies have been carried out to search for other microbial sources for its production.
Detailed explanation-2: -Cyclosporin-A is produced by a fungus called Trichoderma polysporum.
Detailed explanation-3: -Hint: Trichoderma polysporum is a genus belonging to the class under the Kingdom Fungi. This is the most culturable fungi which is grown in all types of soils. It forms endophytic symbiotic relationships with various species of plants. It is a saprophyte and thus is adapted to grow in diverse environmental conditions.
Detailed explanation-4: -Trichoderma polysporum produces cyclosporin A which acts as a immunosuppresant in organ transplant.
Detailed explanation-5: -Cyclosporin lowers the activity of T-cells and hence, suppressing the activity of the immune system. Cyclosporin is isolated from the fungus Trichoderma polysporum.