NEET BIOLOGY

Detailed explanation-1: -The first restriction enzyme to be discovered by Hind II. Hind II was extracted from Haemophilus influenza. Hind II can only recognize a specific site in DNA termed as a recognition site for Hind II (5’-C-A-G-C-T-G-3’).

Detailed explanation-2: -Video Solution: Assertion : The first restriction endonuclease was Hine II Reason :Hind II always cut DNA molecules at a particular point by recongnising a specific sequence of six base pairs.

Detailed explanation-3: -The first Type II REase discovered was HindII from the bacterium Haemophilus influenzae Rd. The event was described by Hamilton Smith (Figure 2) in his Nobel lecture, delivered on 8 December 1978: Figure 2.

Detailed explanation-4: -Hind II was the first restriction endonuclease to be discovered. This enzyme was initially identified from the Rd strain of Haemophilus influenza.

Detailed explanation-5: -In 1978, the Nobel Prize in Physiology or Medicine was awarded jointly to Werner Arber, who predicted the existence of restriction enzymes, Hamilton Smith, who discovered the first Type II restriction enzyme, and Nathans, who demonstrated how to use the restriction enzymes to analyze viral DNA.