NEET BIOLOGY

CELL STRUCTURES AND FUNCTION

BIO MOLECULES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
As food travels through the digestive system, it is exposed to a variety of pH levels. The stomach has a pH of 2 due to the presence of hydrochloride acid (HCl), and the small intestine has a pH ranging from 7 to 9. HCl converts pepsinogen into pepsin, an enzyme that digests proteins in the stomach. Which of the following most likely happens to pepsin as it enters the small intestine?
A
It becomes inactive.
B
It begins to replicate.
C
It’s shape changes to engulf large proteins.
D
It’s activity increases to digest more proteins.
Explanation: 

Detailed explanation-1: -As food travels through the digestive system, it is exposed to a variety of pH levels. The stomach has a pH of 2 due to the presence of hydrochloride acid (HCl), and the small intestine has a pH ranging from 7 to 9. HCl converts pepsinogen into pepsin, an enzyme that digests proteins in the stomach.

Detailed explanation-2: -The intraluminal pH is rapidly changed from highly acid in the stomach to about pH 6 in the duodenum. The pH gradually increases in the small intestine from pH 6 to about pH 7.4 in the terminal ileum. The pH drops to 5.7 in the caecum, but again gradually increases, reaching pH 6.7 in the rectum.

Detailed explanation-3: -Pepsin is a stomach enzyme that serves to digest proteins found in ingested food. Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin.

Detailed explanation-4: -If the acidic environment of the stomach is not maintained at the proper pH, we are unable to absorb minerals, proteins, and vitamins necessary for all the metabolic functions of the body. We can’t make enzymes that catalyze (speed up or facilitate) digestion.

Detailed explanation-5: -Answer and Explanation: Drastic changes in pH in the digestive tract occur due to the presence of acids and bicarbonates which are essential for the activation of digestive enzymes needed for the optimum digestive process.

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