NEET BIOLOGY

CELL STRUCTURES AND FUNCTION

BIO MOLECULES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
can a change in pH alter the active site of an enzyme
A
yes
B
no
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Enzymes are also sensitive to pH . Changing the pH of its surroundings will also change the shape of the active site of an enzyme. Many amino acids in an enzyme molecule carry a charge . Within the enzyme molecule, positively and negatively charged amino acids will attract.

Detailed explanation-2: -Active site amino acid residues often have acidic or basic properties that are important for catalysis. Changes in pH can affect these residues and make it hard for substrates to bind. Enzymes work best within a certain pH range, and, as with temperature, extreme pH values (acidic or basic) can make enzymes denature.

Detailed explanation-3: -So, why does pH affect enzyme activity? pH affects enzyme activity because enzymes are proteins that get their molecular structure via interactions between the charges of the amino acids that form the protein chains. These interactions are in the form of a hydrogen bond which is affected by the pH level.

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