NEET BIOLOGY

Detailed explanation-1: -In the lock-and-key model, the enzyme-substrate interaction suggests that the enzyme and the substrate possess specific complementary geometric shapes that fit exactly into one another.

Detailed explanation-2: -A Lock and Key analogy may be used to describe the fundamental action of a single substrate enzyme. In this case, the enzyme is the lock, and the substrate is the key. Only the correct size key, which is the substrate, enters the keyhole, which is the active site of the lock, which is the enzyme.

Detailed explanation-3: -[The term catalytic mechanism refers to the process whereby enzymes and substrates undergo transformation during catalysis.]

Detailed explanation-4: -The mechanism of action of enzyme inhibitors includes a step of enzyme-inhibitor complex formation (EI complex) that has no (or low) enzyme activity. An irreversible inhibitor dissociates from this complex very slow because it is tightly bound to the enzyme.