NEET BIOLOGY

Detailed explanation-1: -Enzymes work continuously until they are denatured. Enzymes that are no longer active and thus are not able to function are referred to as denatured enzymes. Denaturation of enzymes is caused by extreme temperature and abnormal levels of pH in the body.

Detailed explanation-2: -Enzyme denaturation happens when the structure of a protein and its functional group undergo conformational changes, resulting in inactivity. Denatured proteins have a looser, more random structure, and the majority of them are insoluble.

Detailed explanation-3: -Denaturation is caused by the breaking of the bonds that hold the enzyme together in its three-dimensional shape. Heat can break hydrogen and ionic bonds, which disrupts the shape of the enzyme and will change the shape of the active site.

Detailed explanation-4: -Factors affecting enzyme activity However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-5: -Description. Enzyme activity is at its maximum value at the optimum pH. As the pH value is increased above or decreased below the optimum pH the enzyme activity decreases.