NEET BIOLOGY

Detailed explanation-1: -However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.

Detailed explanation-2: -Enzymes are suited to function best within a certain temperature, pH, and salt concentration range. In addition to high temperatures, extreme pH and salt concentrations can cause enzymes to denature.

Detailed explanation-3: -Chemical induced denaturation Chemical denaturation of the enzyme was performed with increasing concentrations of the denaturant at pH 4.0.

Detailed explanation-4: -At very high or very low pH’s, these bonds within the enzyme can be disrupted, and it can lose its shape. If it loses its shape, the active site will probably be lost completely. This is essentially the same as denaturing the protein by heating it too much.

Detailed explanation-5: -Changes in pH can cause an enzyme to denature (lose their precise shape) and the substrate won’t fit into the active site. Once an enzyme has denatured, it will not function again. The pH at which enzyme activity is highest is known as the optimum pH. Every enzyme will have its own optimum pH.