NEET BIOLOGY

Detailed explanation-1: -Chondroblasts secrete the extracellular matrix which is composed of various substances, including collagen, proteoglycans, glycoproteins, hyaluronic acid, water, and macromolecules. These substances provide strength and structural support to the developing cartilage.

Detailed explanation-2: -Growth plate chondrocytes secrete a cartilage matrix, which is composed of many different proteins, including multiple types of collagen, and proteoglycans.

Detailed explanation-3: -The main cell types in cartilage are chondrocytes, the ground substance is chondroitin sulfate, and the fibrous sheath is called perichondrium.

Detailed explanation-4: -Chondrocytes in the AC proliferate and secrete extracellular matrix to maintain and sustain the cartilage. The cells themselves are separated from each other by cartilage matrix [2]. They respond to outside stimuli and tissue damage, and are also responsible for degenerative conditions, such as osteoarthritis (OA).

Detailed explanation-5: -The ‘ground substance’ of extracellular matrix is an amorphous gelatinous material. It is transparent, colourless, and fills the spaces between fibres and cells. It actually consists of large molecules called glycosoaminoglycans (GAGs) which link together to form even larger molecules called proteoglycans.