NEET BIOLOGY

Detailed explanation-1: -Cancer is a disease caused when cells divide uncontrollably and spread into surrounding tissues. Cancer is caused by changes to DNA. Most cancer-causing DNA changes occur in sections of DNA called genes. These changes are also called genetic changes.

Detailed explanation-2: -Cancer is an uncontrolled growth of cells leading to phenotypic expression in many forms, from mild to life-threatening. Cancer can develop in many ways, either from DNA damage, a mutation in the DNA or any product of that DNA, or by loss of function of the regulatory and repressor systems in the cycle.[9]

Detailed explanation-3: -Cell division and metastasis As time passes, and the cells within the tumor continue to divide and often secrete proteases then break down the extracellular matrix at the boundary of the tissue. At this point, cancer can break free from the confines of the original tissue and infiltrate the surrounding tissue.

Detailed explanation-4: -What is cancer? Cancer is essentially a disease of mitosis-the normal ‘checkpoints’ regulating mitosis are ignored or overridden by the cancer cell. Cancer begins when a single cell is transformed, or converted from a normal cell to a cancer cell.

Detailed explanation-5: -With increasing cell growth, cancer cells spread or infiltrate to involve other organs, displacing normal tissue and severely depleting nutrient and metabolic resources, which results in death either from cancer cachexia or from mechanical disruption of normal organ function.