NEET BIOLOGY

Detailed explanation-1: -Apoptosis can’t kill which of the following? Explanation: Improper regulation of apoptosis is the main cause of proliferative cell growth like cancer. Thus apoptosis can’t actually occur in cancer cells. Other options are types of cells where apoptosis occurs.

Detailed explanation-2: -Many oncogenic stresses, including uncontrolled proliferation or DNA damage, trigger apoptosis; consequently, by culling cells at risk of transformation, apoptosis effectively prevents cancer. Apoptosis also suppresses tumourigenesis in various other ways.

Detailed explanation-3: -Apoptosis is the process of programmed cell death. It is used during early development to eliminate unwanted cells; for example, those between the fingers of a developing hand. In adults, apoptosis is used to rid the body of cells that have been damaged beyond repair. Apoptosis also plays a role in preventing cancer.

Detailed explanation-4: -Cancer cells often have the ability to evade apoptosis, despite damage. This is often because of a nonfunctional p53 protein or an upregulation of anti-apoptotic members of the Bcl-2 family.

Detailed explanation-5: -Cancer cells can ignore the signals that tell them to self destruct. So they don’t undergo apoptosis when they should. Scientists call this making cells immortal.