CELL STRUCTURES AND FUNCTION
CELL CYCLE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Checks for cell size, nutrients, growth factors, and DNA damage.
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G1 checkpoint
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G2 checkpoint
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Spindle checkpoint
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DNA polymerase
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Explanation:
Detailed explanation-1: -At the G1 checkpoint, cells decide whether or not to proceed with division based on factors such as: Cell size. Nutrients. Growth factors. DNA damage.
Detailed explanation-2: -This unleashes cyclin E-CDK2 and cyclin A-CDK2 activity, allowing further RB phosphorylation, exit from G1 and entry into S phase. The G1/S checkpoint is activated upon detection of DNA damage.
Detailed explanation-3: -For example, the G1 checkpoint ensures that the size of the cell is large enough to progress into the S phase and checks for the presence of DNA damage [26].
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