NEET BIOLOGY

CELL STRUCTURES AND FUNCTION

CELL CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Checks for cell size, nutrients, growth factors, and DNA damage.
A
G1 checkpoint
B
G2 checkpoint
C
Spindle checkpoint
D
DNA polymerase
Explanation: 

Detailed explanation-1: -At the G1 checkpoint, cells decide whether or not to proceed with division based on factors such as: Cell size. Nutrients. Growth factors. DNA damage.

Detailed explanation-2: -This unleashes cyclin E-CDK2 and cyclin A-CDK2 activity, allowing further RB phosphorylation, exit from G1 and entry into S phase. The G1/S checkpoint is activated upon detection of DNA damage.

Detailed explanation-3: -For example, the G1 checkpoint ensures that the size of the cell is large enough to progress into the S phase and checks for the presence of DNA damage [26].

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