CELL STRUCTURES AND FUNCTION
CELL CYCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The cell is overriding the cell cycle checkpoints
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The cell is ignoring that it isn’t getting a strong and sustained signal to divide.
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The cell is initiating angiogenesis to get more nutrients.
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The cell refuses to commit apoptosis if the cell has a big problem with its DNA or its metaphase checkpoint,
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Detailed explanation-1: -If the damage is irreparable, the cell may undergo apoptosis, or programmed cell death 2. This self-destruction mechanism ensures that damaged DNA is not passed on to daughter cells and is important in preventing cancer.
Detailed explanation-2: -The M checkpoint determines whether all the sister chromatids are correctly attached to the spindle microtubules before the cell enters the irreversible anaphase stage.
Detailed explanation-3: -The checkpoint is to ensure the cell has grown enough and has enough resources to begin DNA replication. The next checkpoint is the G2 checkpoint, where the cell checks and makes sure the DNA replicated correctly before beginning mitosis. If the cell does not pass this checkpoint, it commences apoptosis and dies.
Detailed explanation-4: -Meiotic checkpoints ensure the production of gametes with the correct complement and integrity of DNA; in metazoans these pathways sense errors and transduce signals to trigger apoptosis to eliminate damaged germ cells.
Detailed explanation-5: -Tumors often acquire mutations that disable checkpoints and cancer cells can therefore progress unimpeded into S-phase, through G2 and into mitosis with chromosomal DNA damage.