CELL STRUCTURES AND FUNCTION
CELL CYCLE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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cyclins
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stem cells
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cyclin-dependent kinases
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both cyclins and cyclin-dependent kinases
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Detailed explanation-1: -Cyclins drive the events of the cell cycle by partnering with a family of enzymes called the cyclin-dependent kinases (Cdks). A lone Cdk is inactive, but the binding of a cyclin activates it, making it a functional enzyme and allowing it to modify target proteins.
Detailed explanation-2: -Summary. Cyclin-dependent kinases (CDKs) are protein kinases characterized by needing a separate subunit-a cyclin-that provides domains essential for enzymatic activity. CDKs play important roles in the control of cell division and modulate transcription in response to several extra-and intracellular cues.
Detailed explanation-3: -Cyclin dependent kinase 20 (CDK20) and p21Cip1/Waf1 are widely recognized as key regulators of cell cycle checkpoints controlling cell proliferation/growth and involving in developing multiple cancers.
Detailed explanation-4: -The activities of cyclin-dependent kinases (Cdks) control all aspects of cell division, including entry into the cell cycle from quiescence, the G1/S phase transition, DNA replication in S phase, nuclear breakdown, chromosome condensation and segregation, and cytokinesis (1).