CELL STRUCTURES AND FUNCTION
CELL CYCLE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
G2 checkpoint
|
|
G1 checkpoint
|
|
M checkpoint
|
|
G1, G2, and M checkpoints
|
Detailed explanation-1: -G2/M checkpoints include the checks for damaged DNA, unreplicated DNA, and checks that ensure that the genome is replicated once and only once per cell cycle. If cells pass these checkpoints, they follow normal transition to the M phase.
Detailed explanation-2: -If errors or damage are detected, the cell will pause at the G 2start subscript, 2, end subscript checkpoint to allow for repairs. If the checkpoint mechanisms detect problems with the DNA, the cell cycle is halted, and the cell attempts to either complete DNA replication or repair the damaged DNA.
Detailed explanation-3: -G2 phase, Gap 2 phase, or Growth 2 phase, is the third subphase of interphase in the cell cycle directly preceding mitosis. It follows the successful completion of S phase, during which the cell’s DNA is replicated.
Detailed explanation-4: -G2 checkpoint – DNA quality control After the second growth phase, the cell checks that the DNA was completely and correctly replicated during the S phase. If it passes it enters the M phase, and if it fails it tries to correct the errors. If the cell is unable to repair the DNA, it undergoes apoptosis.