CELL STRUCTURES AND FUNCTION
CELL CYCLE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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is the cell big enough to divide?
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is DNA copied properly?
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are there errors in DNA?
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have chromosomes properly attached to spindle fibers?
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Detailed explanation-1: -The M checkpoint is also known as the spindle checkpoint: here, the cell examines whether all the sister chromatids are correctly attached to the spindle microtubules.
Detailed explanation-2: -M checkpoint – nuclear division setup check It is also called the spindle checkpoint because the cell examines whether all sister chromatids are correctly attached to the spindle microtubules that separate them. If not, the cell pauses mitosis until all sister chromatids have been attached in the right way.
Detailed explanation-3: -During prometaphase, chromosomes attach to microtubules of the mitotic spindle, so that sister chromatids become attached to opposite poles. In metaphase, the condensed chromosomes align at the equatorial plate.
Detailed explanation-4: -The M phase checkpoint ensures that all chromosomes are attached to the mitotic spindle.
Detailed explanation-5: -Solution: In metaphase of M phase, the spindle fibers are implanted into kinetochores of chromosome.