NEET BIOLOGY

Detailed explanation-1: -The mitotic spindle also begins to develop during prophase. As the cell’s two centrosomes move toward opposite poles, microtubules gradually assemble between them, forming the network that will later pull the duplicated chromosomes apart.

Detailed explanation-2: -During prometaphase the microtubules of the mitotic spindle attach to the kinetochores of condensed chromosomes. The kinetochores of sister chromatids are oriented on opposite sides of the chromosome, so they attach to microtubules emanating from opposite poles of the spindle.

Detailed explanation-3: -In prophase of mitosis, specialized regions on centromeres called kinetochores attach chromosomes to spindle fibers. The centromere is the part of a chromosome that links sister chromatids. During mitosis, spindle fibers attach to the centromere via the kinetochore.

Detailed explanation-4: -The mitotic spindle begins to self-assemble in the cytoplasm during prophase. In animal cells, each of the replicated centrosomes nucleates its own array of microtubules, and the two sets of microtubules interact to form the mitotic spindle.

Detailed explanation-5: -During prophase, the complex of DNA and proteins contained in the nucleus, known as chromatin, condenses. The chromatin coils and becomes increasingly compact, resulting in the formation of visible chromosomes.