NEET BIOLOGY

CELL STRUCTURES AND FUNCTION

CELL CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the first checkpoint of the cell cycle?
A
Mitosis checkpoint
B
G1 checkpoint
C
G2 checkpoint
D
None of the above
Explanation: 

Detailed explanation-1: -The G1 checkpoint. The G1 checkpoint is located at the end of G1 phase, before the transition to S phase. If cells don’t pass the G1 checkpoint, they may “loop out” of the cell cycle and into a resting state called G0, from which they may subsequently re-enter G1 under the appropriate conditions.

Detailed explanation-2: -G1 (restriction) checkpoint. The G1 checkpoint, also known as the restriction point in mammalian cells and the start point in yeast, is the point at which the cell becomes committed to entering the cell cycle.

Detailed explanation-3: -G1 (Restriction) Checkpoint The first checkpoint is located at the end of the cell cycle’s G1 phase, just before entry into S phase, making the key decision of whether the cell should divide, delay division, or enter a resting stage. Most cells stop at this stage and enter a resting state called G0.

Detailed explanation-4: -1: Internal Checkpoints During the Cell Cycle: The cell cycle is controlled at three checkpoints. The integrity of the DNA is assessed at the G1 checkpoint. Proper chromosome duplication is assessed at the G2 checkpoint. Attachment of each kinetochore to a spindle fiber is assessed at the M checkpoint.

Detailed explanation-5: -The primary G1/S cell cycle checkpoint controls the commitment of eukaryotic cells to transition through the G1 phase to enter into the DNA synthesis S phase.

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