NEET BIOLOGY

CELL STRUCTURES AND FUNCTION

CELL CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which checkpoint of the cell cycle checks for the proper and complete replication of DNA?
A
G2
B
G1
C
Spindle checkpoint
D
Cytokinesis
Explanation: 

Detailed explanation-1: -At the G2 checkpoint, the cell checks for: DNA damage. DNA replication completeness.

Detailed explanation-2: -G2/M checkpoints include the checks for damaged DNA, unreplicated DNA, and checks that ensure that the genome is replicated once and only once per cell cycle. If cells pass these checkpoints, they follow normal transition to the M phase.

Detailed explanation-3: -The G2-phase checkpoint, also known as G2/M-phase checkpoint, has the function of preventing cells with damaged DNA, lasting from the G1 and S phases or generated in G2, from undergoing mitosis. The mechanisms acting during the G2-phase checkpoint converge on the inhibition of the mitotic complex CDK1-cyclin B.

Detailed explanation-4: -The M checkpoint is also known as the spindle checkpoint, because it determines whether all the sister chromatids are correctly attached to the spindle microtubules.

Detailed explanation-5: -The primary G1/S cell cycle checkpoint controls the commitment of eukaryotic cells to transition through the G1 phase to enter into the DNA synthesis S phase.

There is 1 question to complete.