CELL STRUCTURES AND FUNCTION
CELL DIVISION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Mutations
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Salutations
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RNA
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Mitosis
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Detailed explanation-1: -Mutations in p53 would prevent abnormal cells from dying by apoptosis. Correct. If the mechanism for eliminating abnormal cells is defective, then the cells will continue to divide and further damage their DNA. This process leads to cancer.
Detailed explanation-2: -Increased expression of antiapoptotic proteins like BCL-2 and down regulation of proapoptotic proteins like BAX are two methods for cells to resist apoptosis [2].
Detailed explanation-3: -If apoptosis is for some reason prevented, it can lead to uncontrolled cell division and the subsequent development of a tumor.
Detailed explanation-4: -Abstract. Cell death by apoptosis is exerted by the coordinated action of many different gene products. Mutations in some of them, acting at different levels in the apoptosis process, have been identified as cause or contributing factor for human diseases.