NEET BIOLOGY

Detailed explanation-1: -The two “sister” chromatids are joined at a constricted region of the chromosome called the centromere. During cell division, spindle fibers attach to the centromere and pull each of the sister chromatids to opposite sides of the cell.

Detailed explanation-2: -Kinetochores are protein formations that develop on each chromosome around the centromere, which is a region located near the middle of a chromosome. Other microtubules bind to the chromosome arms or extend to the opposite end of the cell.

Detailed explanation-3: -Sister Chromatids Are Joined Together at Centromeres In addition to their kinetochore-related function, centromeres perform another essential role in mitosis by serving as the sites of sister chromatid cohesion. For accurate mitoses, sister chromatids must remain attached until the spindle checkpoint has been passed.

Detailed explanation-4: -A sister chromatid refers to the identical copies (chromatids) formed by the DNA replication of a chromosome, with both copies joined together by a common centromere. In other words, a sister chromatid may also be said to be ‘one-half’ of the duplicated chromosome. A pair of sister chromatids is called a dyad.

Detailed explanation-5: -centromeres. … that holds together the two chromatids (the daughter strands of a replicated chromosome). The centromere is the point of attachment of the kinetochore, a structure to which the microtubules of the mitotic spindle become anchored.