CELL STRUCTURES AND FUNCTION
CELL DIVISION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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regulate the cell cycle
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produce p53
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cause cancer
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work to heal wounds
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Detailed explanation-1: -Cyclins are a family of proteins that have no enzymatic activity of their own but activate CDKs by binding to them. CDKs must also be in a particular phosphorylation state-with some sites phosphorylated and others dephosphorylated-in order for activation to occur.
Detailed explanation-2: -Two groups of proteins, cyclins and cyclin-dependent kinases (Cdks), are responsible for promoting the cell cycle.
Detailed explanation-3: -Cell cycle progression is regulated in part by the sequential activity of various cyclins. The cyclins are regulatory subunits that bind, activate and provide substrate specificity for their catalytic partner serine-threonine kinases, collectively called cyclin-dependent kinases (Cdks) (reviewed in refs.
Detailed explanation-4: -Cyclin is a family of proteins that controls the progression of a cell through the cell cycle by activating cyclin-dependent kinase (CDK) enzymes or group of enzymes required for synthesis of cell cycle.
Detailed explanation-5: -Cyclin A is a pivotal regulatory protein which, in mammalian cells, is involved in the S phase of the cell cycle. Transcription of the human cyclin A gene is cell cycle regulated.