NEET BIOLOGY

Detailed explanation-1: -During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids (see Figure below). The sister chromatids line up at the equator, or center, of the cell. This is also known as the metaphase plate.

Detailed explanation-2: -Metaphase: During metaphase, each of the 46 chromosomes line up along the center of the cell at the metaphase plate. Anaphase: During anaphase, the centromere splits, allowing the sister chromatids to separate.

Detailed explanation-3: -Long protein fibers called microtubules extend from the centrioles in all possible directions, forming what is called a spindle. Some of the microtubules attach the poles to the chromosomes by connecting to protein complexes called kinetochores.

Detailed explanation-4: -Centromere The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). Specifically, it is the region where the cell’s spindle fibers attach.

Detailed explanation-5: -Metaphase (the shortest phase of mitosis) is characterized by two events: Chromosomes line up across the middle of the cell. Spindle fibers connect the centromere of each sister chromatid to the poles of the cell.