NEET BIOLOGY

Detailed explanation-1: -Cyclins are proteins that regulate the timing of the cell cycle in eukaryotic cells. Regulatory proteins are proteins that control the cell cycle both inside and outside of the cell. Internal regulators allow the cell cycle to proceed when certain events have occurred INSIDE a cell.

Detailed explanation-2: -Cyclins are a family of proteins that regulate the timing of the cell cycle in eukaryotic cells.

Detailed explanation-3: -Cell cycle progression is regulated in part by the sequential activity of various cyclins. The cyclins are regulatory subunits that bind, activate and provide substrate specificity for their catalytic partner serine-threonine kinases, collectively called cyclin-dependent kinases (Cdks) (reviewed in refs.

Detailed explanation-4: -The core eukaryotic cell cycle control system is based on S phase and mitosis being controlled by cyclin-dependent kinases (CDKs) complexed with S phase cyclins (S-CDKs) and mitotic cyclins (M-CDKs), respectively1, 2.

Detailed explanation-5: -Cyclins regulate the activity of their Cdk partners and also modulate their substrate specificity. More than 20 Cdk-related proteins and more than 11 cyclins have been identified in more complex eukaryotes, which has led to the concept that different cell cycle events are regulated by distinct cyclin-Cdk complexes.