NEET BIOLOGY

CELL STRUCTURES AND FUNCTION

CELL DIVISION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Protein ____ are enzymes that activate or deactivate other proteins by phosphorylating them. To be active, each ____ must be attached to a ____, a protein that gets its name from its cyclically fluctuating concentration in the cell
A
cyclin, kinases, enzyme
B
enzymes, kinases, cyclin
C
kinases, kinases, cyclin
D
None of the above
Explanation: 

Detailed explanation-1: -Protein kinases (PTKs) are enzymes that regulate the biological activity of proteins by phosphorylation of specific amino acids with ATP as the source of phosphate, thereby inducing a conformational change from an inactive to an active form of the protein.

Detailed explanation-2: -Cyclin-dependent kinase (CDK) is a positive regulator that phosphorylates other proteins when activated.

Detailed explanation-3: -CDKs are a family of multifunctional enzymes that can modify various protein substrates involved in cell cycle progression. Specifically, CDKs phosphorylate their substrates by transferring phosphate groups from ATP to specific stretches of amino acids in the substrates.

Detailed explanation-4: -The central components of the cell-cycle control system are cyclin-dependent protein kinases (Cdks), whose activity depends on association with regulatory subunits called cyclins. Oscillations in the activities of various cyclin-Cdk complexes leads to the initiation of various cell-cycle events.

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