NEET BIOLOGY

Detailed explanation-1: -In animal cells, the assembly of spindle microtubules starts at the centrosome. What is another name for the centrosome? The microtubule-organizing center is another name for the centrosome.

Detailed explanation-2: -The mitotic spindle begins to self-assemble in the cytoplasm during prophase. In animal cells, each of the replicated centrosomes nucleates its own array of microtubules, and the two sets of microtubules interact to form the mitotic spindle.

Detailed explanation-3: -The centrosome serves as the initiation site for the assembly of microtubules, which grow outward from the centrosome toward the periphery of the cell.

Detailed explanation-4: -Microtubules are made up of repeating units of /-tubulin heterodimers, which are assembled on a -tubulin ring complex (a complex of -tubulin and other protein components), during the nucleation phase.

Detailed explanation-5: -Prophase is the first stage of mitosis. In prophase, chromosomes condense and become visible. spindle fibers emerge from the centrosomes.