NEET BIOLOGY

Detailed explanation-1: -A gene variant is a permanent change in the DNA sequence that makes up a gene. This type of genetic change used to be known as a gene mutation, but because changes in DNA do not always cause disease, it is thought that gene variant is a more accurate term.

Detailed explanation-2: -A gene mutation (myoo-TAY-shun) is a change in one or more genes. Some mutations can lead to genetic disorders or illnesses.

Detailed explanation-3: -Mutations include changes as small as the substitution of a single DNA building block, or nucleotide base, with another nucleotide base. Meanwhile, larger mutations can affect many genes on a chromosome. Along with substitutions, mutations can also be caused by insertions, deletions, or duplications of DNA sequences.

Detailed explanation-4: -Mutations are changes that occur in DNA or RNA. Mutations can be silent, meaning they have no effect on the protein made, due to redundancy in the genetic code.