NEET BIOLOGY

Detailed explanation-1: -Recessive: A condition that appears only in individuals who have received two copies of a mutant gene, one copy from each parent. The individuals with a double dose of the mutated gene are called homozygotes.

Detailed explanation-2: -An autosomal recessive disorder means two copies of an abnormal gene must be present in order for the disease or trait to develop.

Detailed explanation-3: -Recessive diseases are single gene disorders that only occur in the homozygous state – when an individual carries two mutant versions (alleles) of the relevant gene.

Detailed explanation-4: -To have an autosomal recessive disorder, you inherit two changed genes, sometimes called mutations. You get one from each parent. Their health is rarely affected because they have only one changed gene. Two carriers have a 25% chance of having an unaffected child with two unaffected genes (left).

Detailed explanation-5: -Some of the more common single-gene disorders include cystic fibrosis, hemochromatosis, Tay-Sachs, and sickle cell anemia. Even though these diseases are primarily caused by a single gene, several different mutations can result in the same disease but with varying degrees of severity and phenotype.