NEET BIOLOGY

GENETICS AND EVOLUTION

GENETIC BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Colorblindness is a recessive x-linked disorder. Which genotype represents a male with normal vision?
A
XNXN
B
XnXn
C
XNY
D
XnY
Explanation: 

Detailed explanation-1: -Let (Xc) represent the recessive allele that causes colorblindness and (X+) represent the normal dominant allele. Females that are X+X+ or X+Xc have normal color vision, while XcXc females are colorblind. Males that are X+Y have normal color vision, while XcY males are colorblind.

Detailed explanation-2: -Examples of X-linked recessive conditions include red-green color blindness and hemophilia A: Red-green color blindness. Red-green color blindness means that a person cannot distinguish shades of red and green (usually blue-green), but their ability to see is normal.

Detailed explanation-3: -X-linked recessive pedigree. Marriage between a male with an X-linked recessive trait (aY) and an unaffected woman (AA) produces children with one of two genotypes. All of the sons will are AY, with the Y chromosome from the father and an A allele from the mother.

Detailed explanation-4: -Colour blindness is a X linked recessive disorder in which the eye fails to distinguish between red and green colours. If a colour blind woman with genotype (XCXC) marries a normal visioned man (XY).

Detailed explanation-5: -Answer and Explanation: The genotype for a woman with hemophilia will be: XhXh. Where ‘Xh’ means gene carrying the mutation for hemophilia present in the X chromosome.

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