NEET BIOLOGY

Detailed explanation-1: -A female with a hemophilia allele on one X chromosome usually has a normal allele on her other X chromosome that can produce normal clotting factor, so she has some protection against having hemophilia. A female with one hemophilia allele and one normal allele is called heterozygous or a carrier.

Detailed explanation-2: -Hemophilia is an X-linked recessive hereditary disorder that classically affects males due to the presence of only one X chromosome in males. Females are usually carriers due to the presence of counterpart X chromosome, but many times manifestations of hemophilia are seen in heterozygous carrier females.

Detailed explanation-3: -Hemophilia Carriers A female who inherits one affected X chromosome becomes a “carrier” of hemophilia. She can pass the affected gene on to her children. In addition, a female who is a carrier sometimes can have symptoms of hemophilia. In fact, some doctors describe these women as having mild hemophilia.

Detailed explanation-4: -Hemophilia is a sex-linked recessive disorder. The abnormal gene responsible for hemophilia is carried on the X chromosome.