GENETICS AND EVOLUTION
GENETIC BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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XHXh
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XhXh
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XHY
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XhY
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Detailed explanation-1: -Hemophilia is an X-linked recessive hereditary disorder that classically affects males due to the presence of only one X chromosome in males. Females are usually carriers due to the presence of counterpart X chromosome, but many times manifestations of hemophilia are seen in heterozygous carrier females.
Detailed explanation-2: -Answer and Explanation: The genotype for a woman with hemophilia will be: XhXh. Where ‘Xh’ means gene carrying the mutation for hemophilia present in the X chromosome.
Detailed explanation-3: -The X and Y chromosomes, also known as the sex chromosomes, determine the biological sex of an individual: females inherit an X chromosome from the father for a XX genotype, while males inherit a Y chromosome from the father for a XY genotype (mothers only pass on X chromosomes).