NEET BIOLOGY

Detailed explanation-1: -If a male who has an X linked condition has a son, his son will never inherit the changed gene on the X chromosome. This is because men always pass on their Y chromosome to their sons (if they passed on their X chromosome they would have a daughter).

Detailed explanation-2: -However, if he has an X-linked dominant condition his daughter will be affected. A male will never pass on the changed gene on the X chromosome to his son because his son inherits his Y chromosome (not the X chromosome). A changed gene cannot be corrected, it is present for life.

Detailed explanation-3: -Male-to-male transmission does not exist, as a man never passes his X chromosome to his sons. All daughters of an affected man will inherit the mutant gene. Women who are carriers have a 50% chance of passing the mutant gene to their sons.

Detailed explanation-4: -Because it is unlikely that females will have two altered copies of this gene, males are affected by X-linked recessive disorders much more frequently than females. A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons (no male-to-male transmission).