NEET BIOLOGY

GENETICS AND EVOLUTION

GENETIC BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Sex determination in mammals is determined by the ____ in the ____ chromosome.
A
SRY gene; X
B
SRY gene; Y
C
HERC2; 15
D
BRCA1; 6
Explanation: 

Detailed explanation-1: -This gene is called SRY (sex-determining region of the Y chromosome), and there is extensive evidence that it is indeed the gene that encodes the human testis-determining factor. SRY is found in normal XY males and in the rare XX males, and it is absent from normal XX females and from many XY females.

Detailed explanation-2: -The SRY gene provides instructions for making a protein called the sex-determining region Y protein. This protein is involved in male-typical sex development, which usually follows a certain pattern based on an individual’s chromosomes. People usually have 46 chromosomes in each cell.

Detailed explanation-3: -The SRY gene (blue band) on the male Y chromosome regulates sex determination in mammals. In placental mammals, the presence of a Y chromosome determines sex. Normally, cells from females contain two X chromosomes, and cells from males contain an X and a Y chromosome.

Detailed explanation-4: -In mammals, SRY has been identified in only marsupial and eutherian mammals [12, 13]. This means that SRY evolved in an ancestor of Theria (marsupial and eutherian mammals). This is consistent with the observation that SRY does not exist in Monotremata (monotremes) such as platypuses and echidnas [12, 13].

Detailed explanation-5: -Because only males have the Y chromosome, the genes on this chromosome tend to be involved in male sex determination and development. Sex is determined by the SRY gene, which is responsible for the development of a fetus into a male.

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