NEET BIOLOGY

GENETICS AND EVOLUTION

GENETIC BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is the evidence used mainly in the construction of a linkage map?
A
Rf value
B
Crossover value
C
RQ value
D
Microscopy
Explanation: 

Detailed explanation-1: -Recombination frequency. Recombination frequency is a measure of genetic linkage and is used in the creation of a genetic linkage map. Recombination frequency () is the frequency with which a single chromosomal crossover will take place between two genes during meiosis.

Detailed explanation-2: -The frequency of crossing over between any two linked genes is proportional to the chromosomal distance between them, crossing over frequencies are used to construct genetic or linkage, maps of genes on chromosomes.

Detailed explanation-3: -Several molecular markers such as express sequence tag (EST), single sequence repeats (SSR), restriction fragment length polymorphism (RFLP), amplified fragment length polymorphism (AFLP), randomly amplified polymorphic DNA (RAPD) and single nucleotide polymorphism (SNP) can be used to construct a genetic linkage map.

Detailed explanation-4: -Detection of linkage by PD/NPD ratio Test cross or back cross is performed in order to obtain PD/NPD ratio. If there is ratio of 1 between PD and NPD, then genes are not linked. If this ratio is more than 1, then the genes are linked. It gives almost value of 1.

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