NEET BIOLOGY

GENETICS AND EVOLUTION

GENETIC BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which statement is true of carriers? Select all that apply (there could be multiple possible correct answers).
A
They can pass a recessive disorder gene on to offspring.
B
They express the recessive trait.
C
They have one dominant allele.
D
They are heterozygous for a recessive disorder gene.
Explanation: 

Detailed explanation-1: -Recessive inheritance means both genes in a pair must be abnormal to cause disease. People with only one defective gene in the pair are called carriers. These people are most often not affected with the condition. However, they can pass the abnormal gene to their children.

Detailed explanation-2: -Heterozygotes, with only one mutated allele, are clinically normal carriers of the trait. Homozygous animals usually have clinical disease, and the onset is usually early in life.

Detailed explanation-3: -In a heterozygous genotype, the dominant allele overrules the recessive one. Therefore, the dominant trait will be expressed. The recessive trait won’t show, but you’re still a carrier. This means you can pass it on to your children.

Detailed explanation-4: -A carrier, as related to genetics, is an individual who “carries” and can pass on to its offspring a genomic variant (allele) associated with a disease (or trait) that is inherited in an autosomal recessive or sex-linked manner, and who does not show symptoms of that disease (or features of that trait).

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