NEET BIOLOGY

GENETICS AND EVOLUTION

INHERITANCE AND VARIATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Polydactyly is a condition which results in extra toes in mice. It is controlled by the dominant form of a gene. The normal phenotype is controlled by the recessive form.A female mouse who is homozygous for the condition and a male mouse who is unaffected produce offspring.What proportion of their children would be expected to have Polydactyly?
A
0%
B
25%
C
50%
D
100%
Explanation: 

Detailed explanation-1: -Polydactyly. Polydactyly is an inherited condition in which a person has extra fingers or toes. It is caused by a dominant allele of a gene. This means it can be passed on by just one allele from one parent if they have the disorder.

Detailed explanation-2: -GLI3 gene mutations can cause several forms of isolated polydactyly. These include postaxial polydactyly type A (PAP-A) and type A/B (PAP-A/B), which are characterized by an extra digit next to the little finger or the small toe.

Detailed explanation-3: -Polydactyly may be passed down in families. This trait involves only one gene that can cause several variations. African Americans, more than other ethnic groups, can inherit a 6th finger. In most cases, this is not caused by a genetic disease.

Detailed explanation-4: -Preaxial (radial/tibial) polydactyly: An extra thumb or big toe. Central polydactyly: An extra finger or toe near the middle digits-between the index, middle or ring fingers or any of the toes that aren’t the big or pinkie toe. Postaxial (ulnar/fibular) polydactyly: An extra pinkie finger or toe.

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