NEET BIOLOGY

Detailed explanation-1: -A person with CF inherits two mutated copies of the CFTR gene. These mutations can either be homozygous, the same, or heterozygous, different mutations. The most common mutation is delta F508, accounting for approximately 70% of all mutations.

Detailed explanation-2: -Someone who is heterozygous (Ff) or homozygous (FF) for the dominant allele will not develop cystic fibrosis. In example one, both parents are heterozygous Ff – they are carriers of the disease. This means they have the cystic fibrosis allele and might pass it on to their children.

Detailed explanation-3: -This means that your baby is a carrier of a changed CF gene. A carrier does not have the disease cystic fibrosis. A carrier will not develop signs or symptoms of cystic fibrosis. However, as a parent of a cystic fibrosis carrier, you may still be at risk to have a child who has cystic fibrosis in a future pregnancy.

Detailed explanation-4: -To have cystic fibrosis, a child must inherit one copy of the cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation from each parent. People who have only one copy of a CFTR gene mutation do not have CF. They are called “CF carriers."