NEET BIOLOGY

Detailed explanation-1: -In humans, polydactyly (i.e, presence of extra fingers and toes) is determined by a dominant autosomal allele (P) and the normal condition is determined by a recessive allele (p).

Detailed explanation-2: -GLI3 gene mutations can cause several forms of isolated polydactyly. These include postaxial polydactyly type A (PAP-A) and type A/B (PAP-A/B), which are characterized by an extra digit next to the little finger or the small toe.

Detailed explanation-3: -Polydactyly is due to a dominant allele that is incompletely penetrant in heterozygotes. The Penetrance value for this trait is currently estimated to be 0.8. Two phenotypically normal individuals are heterozygous for this gene and considering starting a family.

Detailed explanation-4: -Polydactyly of Index Fingers (Preaxial Polydactyly Type 3) Preaxial polydactyly type 3 (MIM 174600) is very rare disorder segregating in an autosomal dominant fashion. In this type, the index finger is usually duplicated. One or two triphalangeal digits replace the thumb.

Detailed explanation-5: -Polydactyly is an inherited condition in which a person has extra fingers or toes. It is caused by a dominant allele of a gene. This means it can be passed on by just one allele from one parent if they have the disorder.