GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Okazaki Fragments
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Helicase
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Leading Strand
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Replication Fork
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Detailed explanation-1: -Because of its Y-shaped structure, this active region is called a replication fork (Figure 5-6). At a replication fork, the DNA of both new daughter strands is synthesized by a multienzyme complex that contains the DNA polymerase.
Detailed explanation-2: -The separation of the two single strands of DNA creates a ‘Y’ shape called a replication ‘fork’. The two separated strands will act as templates for making the new strands of DNA.
Detailed explanation-3: -Each end of the bubble is a replication fork, a Y-shaped junction where double-stranded DNA is separated into two single strands. New DNA complementary to each single strand is synthesized at each replication fork.
Detailed explanation-4: -An enzyme called helicase unwinds the DNA by breaking the hydrogen bonds between the nitrogenous base pairs. ATP hydrolysis is required for this process. As the DNA opens up, Y-shaped structures called replication forks are formed.
Detailed explanation-5: -Replication bubble is a structure formed by the separation of two DNA strands by the helicase enzymes. Replication fork is a two line fork or prong-like structure that is formed in the replication bubble.