GENETICS AND EVOLUTION
MOLECULAR BASIS OF INHERITANCE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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phenotypes that prevent fertilization.
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death during pupation.
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failure to express maternal effect genes.
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phenotypes that are never born/hatched.
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Detailed explanation-1: -Embryonic lethality is a common phenotype that occurs in mice that are homozygous for genetically engineered mutations. These phenotypes highlight the time and place that a gene is first required during embryogenesis.
Detailed explanation-2: -Early embryonic lethality caused by genetically engineered mutations have led to great insights into the genetic control of fundamental biological processes, including cell division, cell death, cell fate, differentiation, and morphogenesis.
Detailed explanation-3: -Lethal mutations usually stem from lethal genes or alleles. Depending on the genes involved, fatal genes can be dominant, recessive, or even conditional. The death of an entity can occur at any moment, with the most prevalent occurrence being during the early phases of development.
Detailed explanation-4: -Embryonic lethality is a recognized phenotypic expression of individual gene mutations in model organisms. However, identifying embryonic lethal genes in humans is challenging, especially when the phenotype is manifested at the preimplantation stage.