NEET BIOLOGY

GENETICS AND EVOLUTION

MOLECULAR BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
If the base sequence of a codon in mRNA is 5’-AUG-3’ the sequence of tRNA pairing with it must be
A
5’-UAC-3’
B
5’-CAU-3’
C
5’-AUG-3’
D
5’-GUA-3’
Explanation: 

Detailed explanation-1: -The first base of the anticodon in 5’-3’ direction binds with the third base in codon (reading in 5’-3’ direction). Thus, if the base sequence in codon of mRNA is 5’-AUG-3’, the complementary anticodon will be3’-UAC-5’ or 5’-CAU-3’.

Detailed explanation-2: -At one end, the tRNA has an anticodon of 3’-UAC-5’, and it binds to a codon in an mRNA that has a sequence of 5’-AUG-3’ through complementary base pairing. The other end of the tRNA carries the amino acid methionine (Met), which is the the amino acid specified by the mRNA codon AUG.

Detailed explanation-3: -Therefore the anticodon for the tRNA for the mRNA codon 5’ GCA 3’ will be 3’ CGU 5’.

Detailed explanation-4: -Answer and Explanation: If the anticodon on a tRNA is 5’ GUA 3’ the codon is 3’ UAC 5’. The 5’ GUA 3’ anticodon is complementary to the 3’ UAC 5’ codon. the mRNA codon UAC codes for Tyrosine.

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