NEET BIOLOGY

GENETICS AND EVOLUTION

MOLECULAR BASIS OF INHERITANCE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In eukaryotic cells, transcription cannot begin until ____
A
the two DNA strands have completely separated and exposed the promoter.
B
several transcription factors have bound to the promoter.
C
the 5’ caps are removed from the mRNA.
D
the DNA introns are removed from the template.
Explanation: 

Detailed explanation-1: -In eukaryotic cells, transcription cannot begin until. the two DNA strands have completely separated and exposed the promoter. several transcription factors have bound to the promoter.

Detailed explanation-2: -Eukaryotic transcription is carried out in the nucleus of the cell and proceeds in three sequential stages: initiation, elongation, and termination. Eukaryotes require transcription factors to first bind to the promoter region and then help recruit the appropriate polymerase.

Detailed explanation-3: -Many eukaryotic genes have a conserved promoter sequence called the TATA box, located 25 to 35 base pairs upstream of the transcription start site. Transcription factors bind to the TATA box and initiate the formation of the RNA polymerase transcription complex, which promotes transcription.

Detailed explanation-4: -Eukaryotic transcription factors (TF) function by binding to short 6-10 bp DNA recognition sites located near their target genes, which are scattered through vast genomes.

Detailed explanation-5: -Learning Outcomes. Like prokaryotic cells, the transcription of genes in eukaryotes requires the action of an RNA polymerase to bind to a DNA sequence upstream of a gene in order to initiate transcription.

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